Marka la barbardhigo PRP, ma jiraan wax lagu daro dibadda ah oo loo isticmaalo diyaarinta PRF, taas oo ka fogaanaysa khatarta diidmada difaaca, caabuqa isdhaafka ah iyo xinjirowga dhiigga oo xumaada.Tignoolajiyada diyaarinteeda waa la fududeeyay.Waa hal-tallaabo centrifugation, kaas oo u baahan kaliya in lagu xareeyo xawaare hoose ka dib marka dhiiga la geliyo tuubada centrifuge.Qaybta silikon ee tuubada centrifuge galaas waxay kor u qaadaa polymerization physiological ee firfircoonida platelet iyo fibrin, jilitaanka habka xinjirowga jireed ayaa la bilaabay waxaana la ururiyaa xinjiro dabiici ah.
Marka loo eego aragtida ultrastructure, waxa la ogaaday in is waafajinta kala duwan ee qaab dhismeedka reticular-ka ee fibrin uu yahay qaabka ugu muhiimsan ee labada weji, waxayna caddahay inay ku kala duwan yihiin cufnaanta iyo nooca.Cufnaanta fibriinka waxaa lagu go'aamiyaa tirada alaabta ceeriin ee fibrinogen, nooceeduna waxay ku xiran tahay wadarta tirada thrombin iyo heerka polymerization.Habka diyaarinta ee PRP-dhaqameedka, fibriinka polymerized ayaa si toos ah loo tuuray sababtoo ah kala diritaankeeda PPP.Sidaa darteed, marka thrombin lagu daro tillaabada saddexaad si kor loogu qaado xinjirowga, waxa ku jira fibrinogen si weyn ayaa loo dhimay, sidaas darteed cufnaanta qaab dhismeedka shabakadda ee fibrin polymerized ayaa aad uga hooseeya kan xinjirowga dhiigga physiological, sababtoo ah saameynta Exogenous Waxyaalaha lagu daro, fiirsashada xinjirowga sare ee xinjirowga ayaa ka dhigaya xawaaraha polymerization ee fibrinogen aad uga sarreeya kan falcelinta jireed.Shabakadda fibrin ee la sameeyay waxaa sameeyay polymerization ee afar unug oo fibrinogen ah, kuwaas oo adag iyo la'aan la'aan, taas oo aan ku habboonayn ururinta cytokines iyo kor u qaadista socdaalka unugyada.Sidaa darteed, qaan-gaarnimada shabakada fibrin ee PRF ayaa ka fiican PRP, taas oo ku dhow xaaladda jireed.
