PRP Tube oo leh Gel
Sharaxaad Gaaban:
Abstract.AutologousPlasma qani ku ah platelet(PRP) jel ayaa si sii kordheysa loogu isticmaalaa daaweynta noocyo kala duwan oo jilicsan iyo cilladaha unugyada lafaha, sida dardargelinta sameynta lafaha iyo maareynta nabarrada aan bogsaneynin ee daba-dheeraada.
Dhammaan unugyada dhiigga waxay ka soo jeedaan unugga tarma ee pluripotent caadiga ah, kaas oo u kala sooca xariiqyo unugyo kala duwan.Mid kasta oo ka mid ah taxanahan unuggu waxa uu ka kooban yahay horudhacyo kala qaybin kara oo qaan gaadhi kara.
Platelets, oo sidoo kale loo yaqaan thrombocytes, ayaa ka soo baxa dhuuxa lafta.Platelets waa nukleed, xubno unugyo discoid ah oo leh cabbirro kala duwan iyo cufnaanta qiyaastii 2 μm dhexroor, cufnaanta ugu yar ee dhammaan unugyada dhiigga.Tirada jireed ee platelets ee ku wareegaysa qulqulka dhiiga waxay u dhaxaysaa 150,000 ilaa 400,000 platelet per μL.
Platelets waxay ka kooban yihiin dhowr granules oo sir ah kuwaas oo muhiim u ah shaqada platelet.Waxaa jira 3 nooc oo granules: granules cufan, o-granules, iyo lysosomes.Taxane kasta waxaa ku jira qiyaastii 50-80 granules, oo ah kan ugu badan ee 3 nooc ee granules.
Platelets ayaa ugu horrayn mas'uul ka ah habka isku-darka.Hawsha ugu weyni waa in ay gacan ka geysato homeostasis trough 3 habraac: adhesion, activation, and aggregation.Inta lagu jiro dhaawaca xididada xididada, platelets waa la shaqeyaa, granules-kooduna waxay soo daayaan waxyaabo kor u qaada xinjirowga.
Platelets waxa loo malaynayay inay leeyihiin firfircoonida dhiigbaxa, in kasta oo sannadihii u dambeeyay, cilmi-baadhista sayniska iyo tignoolajiyada ay bixiyeen aragti cusub oo ku saabsan platelets iyo hawlahooda.Daraasaduhu waxay soo jeedinayaan in platelets ay ku jiraan tiro badan oo GFs ah iyo cytokines kuwaas oo saameyn kara bararka, angiogenesis, guuritaanka unugyada stem, iyo kororka unugyada.
PRP waa isha dabiiciga ah ee unugyada calaamadaha, iyo marka la hawlgeliyo platelets gudaha PRP, P-granules waa la daaray oo sii daaya GFs iyo cytokines kuwaas oo wax ka beddeli doona microenvironment unug kasta.Qaar ka mid ah GF-yada ugu muhiimsan ee lagu sii daayo platelets ee PRP waxaa ka mid ah GF endothelial vascular, fibroblast GF (FGF), GF-ka-soo-baxa platelet, epidermal GF, hepatocyte GF, insulin-sida GF 1, 2 (IGF-1, IGF-2), Matrix metalloproteinase 2, 9, iyo interleukin 8.
